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Oral administration of high-dose vitamin B 12 (1 to 2 mg daily) is considered as effective as intramuscular administration for correcting anemia and neurologic symptoms Despite many studies suggesting oral administration of vitamin B 12 to be easy, effective and less costly than intramuscular administration, debate surrounds the effectiveness of the oral route

For instance, you may need antibiotics if your anemia was caused by bad bacteria

Passive diffusion accounts for about 1% of total absorption, and this route of absorption is unaffected in patients with pernicious anemia ( There were studies in the 1950s and the1960s that showed that oral vitamin B12 could be absorbed by patients with pernicious anemia and could lead to resolution of the anemia ( The objective of our review is to inform clinicians on the effectiveness of oral vitamin B12 as adequate replacement in patients with pernicious anemia, as well as make recommendations on the dosing and frequency of clinical and laboratory monitoring

Muhammad Shahzeb Khan, Javed Butler (2019)

Store lyophilized at 20C long-term

Seek emergency medical attention immediately if you experience more severe symptoms, such as difficulty breathing, dizziness, or swelling of the face or throat, as these could be signs of a serious allergic reaction (anaphylaxis)